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Search Results for " chk-1 inhibitor "

6

Compounds

Cat No. Product Name Synonyms Targets
T10793 CHK1 inhibitor GDC-0575 analog Chk
CHK1 inhibitor (GDC-0575 analog) is a CHK1 inhibitor.
T6028 PF 477736 PF 00477736,PF-477736,PF-736,PF-00477736,PF477736 c-Fms , VEGFR , FGFR , FLT , c-RET , Chk , CDK , Src , Aurora Kinase
PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.
T13148 CHK-IN-1 Chk
CHK-IN-1 is a dual inhibitor of CHK1 and CHK2 with antiproliferative activity.
T80132 CBP501 Affinity Peptide
CBP501 Affinity Peptide, a Chk kinase inhibitor, disrupts G2 arrest triggered by DNA-damaging agents and is utilized in cancer research [1].
T79874 CHK-336
CHK-336 (Example 1), an orally active LDHA inhibitor (IC50 <1 nM), suppresses lactate production in mouse hepatocytes and is applicable in hyperoxaluria research [1].
T82393 FLT3/CHK1-IN-1
Compound 18, also known as FLT3/CHK-IN-1, is a dual inhibitor targeting FLT3 and CHK1, exhibiting over 1700-fold selectivity towards c-KIT and significantly diminishing hERG affinity, with an IC50 of 58.4 μM. It demonstr...
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